RADIOLOGICAL ASPECTS OF DEFORMITIES ASSOCIATED WITH RHEUMATOID ARTHRITIS

Authors

  • José Henrique Gorgone Zampieri Autor
  • Eduarda Vieira Frediani Autor
  • Wilton Pereira dos Santos Autor
  • Janaina Zimpel Nascimento Autor
  • Ugo Roberto de Lima Accorsi Autor
  • Sthenio Rocha Soares Autor

DOI:

https://doi.org/10.63330/aurumpub.024-044

Keywords:

Rheumatoid arthritis, Joint deformities, Radiological aspects, Conventional X-ray

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease that primarily affects synovial joints, leading to progressive structural changes whose radiological findings are fundamental for diagnosis, staging, and monitoring. Initial changes may include periarticular osteopenia, resulting from synovial hyperemia and bone demineralization associated with inflammation. As the disease progresses, bone erosions appear – a characteristic finding consisting of the loss of subchondral cortical bone, most frequently in areas of tendon and ligament insertion, such as the metacarpophalangeal and metatarsophalangeal heads. In addition to erosions, synovial thickening and joint effusion are observed, which can be detected by methods such as ultrasound and magnetic resonance imaging (MRI) even before the appearance of changes on conventional radiography. The progression of inflammation leads to changes in joint congruency, with subsequent instability and development of deformities. The most common deformities present recognizable radiological patterns: ulnar deviation of the fingers, with subluxation of the metacarpophalangeal joints; claw toes, resulting from flexion in the proximal phalanx and extension in the distal phalanx; buttonhole, caused by subluxation of the proximal phalanx over the distal phalanx; and hammer toes, resulting from flexion of the distal phalanx. In the foot joints, hallux valgus and claw toe deformities stand out. In advanced stages, there is synostotic fusion of joints, mainly on the backs of the hands and feet, in addition to alterations in large joints such as knees, hips, and shoulders, which may present narrowing of the joint space, subluxation, and avascular necrosis. Conventional radiography remains the initial method of evaluation, while MRI and ultrasound allow early detection of structural lesions. Radiological monitoring assists in evaluating the response to treatment and determining the patient's functional prognosis.

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References

1. Lee DM, Weinblatt ME. Rheumatoid arthritis. Lancet 2001; 358(9285):903–11.

2. Alarcón GS. Epidemiology of rheumatoid arthritis. Rheum Dis Clin North Am 1995; 21(3):589–604.

3. Mota LMH. Atualização em Reumatologia: Artrite reumatoide Inicial. Ver Bras Reumatol 2008; 48(6):360–5.

4. Mota LMH, Carvalho JF, Santos-Neto LL. Autoantibodies and other serological markers in rheumatoid arthritis: predictors of disease activity? Clin Rheumatol 2009; 28(10):1127–34.

5. Keen HI, Emery P. How should we manage early rheumatoid arthritis? From imaging to intervention. Curr Opin Rheumatol 2005; 17(3):280–5.

6. Brown AK, Wakefi eld RJ, Conaghan PG, Karim Z, O’Connor PJ, Emery P. New approaches to imaging early infl ammatory arthritis. Clin Exp Rheumatol 2004; 22(5 Suppl. 35):S18–25.

7. Kubota K, Ito K, Morooka M, Mitsumoto T, Kurihara K, Yamashita H Et al. Whole -body FDG-PET/CT on rheumatoid arthritis of large. Joints. Ann Nucl Med 2009; 23(9):783–91.

8. Basu S, Zhuang H, Torigian DA, Rosenbaum J, Chen W, Alayi A. Functional imaging of infl ammatory diseases using nuclear medicine. Techniques. Semin Nucl Med 2009; 39(2):124–45.

9. Fonseca A, Wagner J, Yamaga LI, Osawa A, da Cunha ML,Scheinberg M. (18) F-FDG PET imaging of rheumatoid articular and extraarticular synovitis. J Clin Rheumatol 2008; 14(5):307.

10. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS et al. The American Rheumatism Association 1987. Revised criteria for the classifi cation of rheumatoid arthritis. Arthritis Rheum 1988; 31(3):315–24.

11. Van der Heijde DM. Radiographic imaging: the “gold standard”. For assessment of disease progression in rheumatoid arthritis. Rheumatology (Oxford) 2000; 39(Suppl. 1):9–16. Dixey J, Solymossy C, Young A; Early RA Study. Is it possible to predict radiological damage in early rheumatoid arthritis. Factors of radiological erosions over the first 3 years in 866

12. Patients from the Early RA Study (ERAS). J Rheumatol Supp, 2004; 69:48–54. Lindqvist E, Jonsson T, Saxne T, Eberhardt K. Course of radiographic damamage over 10 years in a cohort with early rheumatoid arthritis. Ann Rheum Dis 2003; 62(7):611–6.

13. Wakefield RJ, D’Agostino MA, Iagnocco A, Filippucci E, Backhaus M, Scheel AK et al.; OMERACT Ultrasound Group. The OMERACT Ultrasound Group: status of current activities and research directions. J Rheumatol 2007; 34(4):848–51.

14. Fernandes EA, Castro Júnior MR, Mistraud SAV, Kubota ES, Fernandes ARC. Ultrassonografi a na artrite reumatoide: aplicabilidade e perspectives. Ver Bras Reumatol 2008; 48(1):25–30. Østergaard M, Pedersen SJ, Døhn UM. Imaging in rheumatoid – status and recent advances for magnetic resonance .

Published

2026-01-20

How to Cite

Zampieri, J. H. G., Frediani, E. V., dos Santos, W. P., Nascimento, J. Z., Accorsi, U. R. de L., & Soares, S. R. (2026). RADIOLOGICAL ASPECTS OF DEFORMITIES ASSOCIATED WITH RHEUMATOID ARTHRITIS. Aurum Editora, 433-443. https://doi.org/10.63330/aurumpub.024-044

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