GARDASIL 9 AS A STRATEGY FOR ONCOLOGICAL PREVENTIVE MEDICINE: INTEGRATION BETWEEN IMMUNIZATION, SCREENING, AND REDUCTION OF THE GLOBAL BURDEN OF CERVICAL CANCER

Authors

  • Lara Vasconcelos de Melo Amorim Autor
  • Érika Teodoro Alves Moura Autor
  • Juliana Gervásio Silveira Araújo Autor
  • Sttyvie Eugênio Morato de Albuquerque Silva Autor

DOI:

https://doi.org/10.63330/aurumpub.034-022

Keywords:

Cervical cancer, HPV nine-valent vaccine, Immunization, Preventive medicine, Screening

Abstract

This chapter aims to analyze the role of the nine-valent human papillomavirus (HPV) vaccine, commercially known as Gardasil 9, as an oncological preventive medicine strategy, emphasizing its integration with screening programs and public health policies designed to reduce the global burden of cervical cancer. This study consists of a narrative review of national and international scientific literature, adopting a qualitative approach and examining institutional guidelines. The findings indicate that expanding vaccination coverage combined with cytological and molecular screening significantly reduces the incidence of high-grade intraepithelial lesions and mortality associated with cervical cancer. Integrated strategies based on equitable access and health education further enhance immunization outcomes, particularly among vulnerable populations. It is concluded that the systematic incorporation of the nine-valent vaccine into national immunization schedules, aligned with organized screening programs, represents a cost-effective and essential measure to achieve global targets for the elimination of cervical cancer as a public health problem.

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References

BARDIN, Laurence. Análise de conteúdo. São Paulo: Edições 70, 2011.

BRASIL. Ministério da Saúde. Secretaria de Vigilância em Saúde. Diretrizes brasileiras para o rastreamento do câncer do colo do útero. 2. ed. Brasília: Ministério da Saúde, 2016.

BRUNI, Laia et al. Global and regional estimates of genital human papillomavirus prevalence in men and women: a systematic review and meta-analysis. The Lancet Global Health, London, v. 7, n. 4, p. e469–e478, 2019.

JOURA, Elmar A. et al. A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women. New England Journal of Medicine, Boston, v. 372, n. 8, p. 711–723, 2015.

SCHILLER, John T.; LOWY, Douglas R. Raising expectations for subunit vaccine. Journal of Infectious Diseases, Oxford, v. 217, n. 4, p. 569–571, 2018.

WORLD HEALTH ORGANIZATION. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: WHO, 2020.

Published

2026-03-06

Issue

Section

Artigos

How to Cite

GARDASIL 9 AS A STRATEGY FOR ONCOLOGICAL PREVENTIVE MEDICINE: INTEGRATION BETWEEN IMMUNIZATION, SCREENING, AND REDUCTION OF THE GLOBAL BURDEN OF CERVICAL CANCER. (2026). Aurum Editora, 303-310. https://doi.org/10.63330/aurumpub.034-022