ASSOCIATION BETWEEN URTI AND OTITIS MEDIA: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.63330/aurumpub.036-028Keywords:
Viral respiratory infection, Acute otitis media, Tubal dysfunction, Bacterial co-infection, PediatricsAbstract
The following study aimed to evaluate the association between acute viral upper respiratory tract infections (URTIs) and the development of otitis media, synthesizing observational evidence and clinical trials. The methodology applied consisted of a systematic review of studies that investigated the temporal relationship between URTI episodes and otitis media in children and adults. The results showed that most observational studies demonstrated a strong temporal correlation between URTIs and acute otitis media, with plausible pathophysiological mechanisms. The magnitude of the association varied by viral type, age group, and comorbidities. Consistent evidence indicates that URTIs are a significant risk factor for otitis media in pediatric populations, especially in children under 5 years of age; however, methodological gaps limit definitive causal inferences.
Downloads
References
HEIKKINEN, T.; CHONMAITREE, T. Importance of respiratory viruses in acute otitis media. Clinical Microbiology Reviews, Washington, v. 16, n. 2, p. 230–241, 2003.
RUOHOLA, A. et al. Microbiology of acute otitis media in children with tympanostomy tubes: prevalences of bacteria and viruses. Clinical Infectious Diseases, Chicago, v. 43, n. 11, p. 1417–1422, 2006.
CHO, I. et al. Viral-bacterial interactions in acute otitis media. Current Allergy and Asthma Reports, New York, v. 11, n. 6, p. 547–554, 2011.
MONTO, A. S. Epidemiology of viral respiratory infections. The American Journal of Medicine, New York, v. 112, supl. 69, p. 4S–12S, 2002.
TEELE, D. W.; KLEIN, J. O.; ROSNER, B. Epidemiology of otitis media during the first seven years of life in children in greater Boston. The Journal of Infectious Diseases, Chicago, v. 160, n. 1, p. 83–94, 1989.
PARADISE, J. L. et al. Tympanometric detection of middle ear effusion in infants and young children. Pediatrics, Springfield, v. 58, n. 2, p. 198–210, 1976.
HEIKKINEN, T. et al. A prospective study of the incidence of acute otitis media during upper respiratory tract infection. The Pediatric Infectious Disease Journal, Baltimore, v. 18, n. 7, p. 632–635, 1999.
JEFFREY, M. M.; SMITH, A. Viral upper respiratory infection and acute otitis media: a review. Pediatric Clinics of North America, Philadelphia, v. 60, n. 2, p. 391–407, 2013.
BLOCK, S. L. Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. The Pediatric Infectious Disease Journal, Baltimore, v. 16, n. 4, p. 449–456, 1997.
PRINCIPI, N.; ESPOSITO, S. Prevention of acute otitis media by vaccination. Human Vaccines C Immunotherapeutics, Austin, v. 14, n. 7, p. 1683–1689, 2018.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
