POMEGRANATE EXTRACTION AND ITS THERAPEUTIC BENEFITS

Authors

  • Raniely Marina Ferreira de Souza Autor
  • Eduardo da Costa Martins Autor

DOI:

https://doi.org/10.63330/armv2n5-028

Keywords:

Punica granatum, Extraction methods, Bioactive compounds, Therapeutic applications

Abstract

The present work focuses on the study of the extraction methods of the bioactive compounds present in the pomegranate (Punica granatum) and their relevance to human health. The main objective is to describe, in a clear and accessible way, the techniques used to extract active substances from the fruit, such as aqueous, alcoholic and ultrasonic extraction, evidencing the potential of each approach in preserving and obtaining the main bioactive components. The justification for choosing this theme lies in the growing scientific and social interest in the benefits of pomegranate, whose compounds, widely distributed in peel and seeds, demonstrate antioxidant, cardioprotective properties and possible anticancer effects. Approaching extraction methods in a judicious way allows us to identify which techniques are most effective to ensure the chemical integrity of these substances, expanding their applications in pharmaceutical, nutraceutical, and food products. Thus, the study intends to contribute to the understanding of how the efficient use of natural resources can result in concrete advances for health promotion, motivating researchers and professionals in the area to explore the therapeutic potential of pomegranate in an ethical, sustainable and innovative way.

Downloads

Download data is not yet available.

References

ABUTAYEH, R. et al. Identification of punicalagin as a key bioactive compound responsible for antimicrobial properties of pomegranate peel extract. Journal of Agricultural and Food Chemistry, 2024.

AKABERI, Maryam et al. Therapeutic effects of Punica granatum (pomegranate): an updated review of clinical trials. Journal of Nutrition and Metabolism, v. 2021, p. 5297163, 2021. DOI: https://doi.org/10.1155/2021/5297163.

BARRECA, Davide et al. Punica granatum L.: phytochemical composition and biological properties. Plants, Basel, v. 9, n. 4, p. 471, 2020. DOI: https://doi.org/10.3390/plants9040471.

CHENG, X. et al. Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin isolated from Punica granatum. Food and Chemical Toxicology, 2021.

CRUZ-VALENZUELA, Manuel Reynaldo et al. Pomegranate (Punica granatum L.) peel extracts as antimicrobial and antioxidant additives used in alfalfa sprouts. Foods, Basel, v. 11, n. 17, p. 2588, 2022. DOI: https://doi.org/10.3390/foods11172588.

GULLÓN, Beatriz et al. Pomegranate peel as suitable source of high-added value bioactives: Tailored functionalized materials. Molecules, Basel, v. 25, n. 12, p. 2859, 2020. DOI: https://doi.org/10.3390/molecules25122859.

KSHIRSAGAR, Kalyani R.; PATHAK, Swanand S.; PATIL, Sejal M. Pomegranate (Punica granatum L.): a fruitful fountain of remedial potential. Cureus, v. 15, n. 9, e45677, 2023. DOI: 10.7759/cureus.45677.

KORE, P. et al. Phytochemistry and pharmacological properties of Punica granatum: a systematic review. International Journal of Biology, Pharmacy and Allied Sciences, v. 13, n. 2, 2024.

LI, Y. et al. Biodegradation of punicalagin into ellagic acid by selected probiotic bacteria. Journal of Agricultural and Food Chemistry, 2022.

MENA, Pedro et al. Pomegranate polyphenols and their potential role in the prevention of inflammatory diseases. Antioxidants, v. 9, n. 6, 2020.

RANJHA, Muhammad Modassar Ali Nawaz et al. A comprehensive review on phytochemistry, bioactivity and medicinal value of bioactive compounds of pomegranate (Punica granatum). Advances in Traditional Medicine, v. 23, p. 37–57, 2023. DOI: 10.1007/s13596-021-00566-7.

RUAN, Jing-Hui et al. Phenolic compounds and bioactivities from pomegranate (Punica granatum L.) peels. Journal of Agricultural and Food Chemistry, Washington, v. 70, n. 12, p. 3678-3686, 2022. DOI: https://doi.org/10.1021/acs.jafc.1c08341.

SALIM, Amira et al. Identification of punicalagin as a key bioactive compound responsible for the antimicrobial properties of Punica granatum L. peel extract against Staphylococcus aureus. Journal of Agricultural and Food Chemistry, Washington, v. 73, n. 29, p. 18280-18290, 2025. DOI: https://doi.org/10.1021/acs.jafc.5c02320.

SINGH, Bhupinder et al. A unique understanding of traditional medicine of pomegranate, Punica granatum L., and its current research status. Journal of Ethnopharmacology, Amsterdam, v. 271, p. 113877, 2021.

SHRESTHA, S. et al. Inhibitory potential of pomegranate (Punica granatum L.) polyphenols against carbohydrate-digesting enzymes: implications for diabetes management. Journal of Food Biochemistry, v. 48, n. 2, 2024.

TOLEDO-MERMA, Pamela R. et al. Phenolic compounds recovery from pomegranate (Punica granatum L.) by-products by pressurized liquid extraction. Foods, Basel, v. 11, n. 8, p. 1070, 2022. DOI: https://doi.org/10.3390/foods11081070.

ZHANG, L. et al. Traditional uses, phytochemistry and pharmacology of Punica granatum L.: a review. Journal of Ethnopharmacology, v. 268, 2021.

ZHU, G. et al. Study on the effects of tannase on the de-astringency of pomegranate juice. Foods, v. 14, n. 6, 2025.

Published

2026-05-20

How to Cite

de Souza, R. M. F., & Martins, E. da C. (2026). POMEGRANATE EXTRACTION AND ITS THERAPEUTIC BENEFITS. Aurum Revista Multidisciplinar, 2(5), 1-10. https://doi.org/10.63330/armv2n5-028

Publications by the same author

1 2 3 4 > >>