ADVANCES IN BIOMEDICINE FOR THE EARLY DIAGNOSIS OF DISEASES
DOI:
https://doi.org/10.63330/aurumpub.034-001Palabras clave:
Biomedicine, Biomarkers, Early diagnosis, Precision medicineResumen
Early diagnosis is one of the most relevant pillars for reducing morbidity and mortality associated with chronic and infectious diseases. Therefore, this chapter aims to analyze the advances of biomedicine in the early diagnosis of diseases, considering technological and biomolecular innovations applied to clinical practice. The methodology was based on a narrative review of scientific literature, including classical and contemporary studies by authors such as Francis Collins, Eric Topol, Leroy Hood, and Harold Varmus, published in international scientific databases. The results indicate that the use of molecular biomarkers, genomic testing, artificial intelligence, and high-precision imaging technologies has significantly increased the ability to identify pathological changes before the clinical manifestation of symptoms. These advances allow faster, more personalized, and more effective interventions, especially in diseases such as cancer, diabetes, and cardiovascular disorders. It is concluded that the integration of biotechnology, genetics, and computational analysis is transforming early diagnosis into an essential tool of precision medicine, promoting greater therapeutic efficiency, reduced healthcare costs, and improved quality of life for patients.
Descargas
Referencias
BARDIN, Laurence. Análise de conteúdo. São Paulo: Edições 70, 2016.
COLLINS, Francis S.; VARMUS, Harold. A new initiative on precision medicine. New England Journal of Medicine, v. 372, n. 9, p. 793–795, 2015.
HOOD, Leroy; FRIEND, Stephen H. Predictive, personalized, preventive, participatory (P4) cancer medicine. Nature Reviews Clinical Oncology, v. 8, n. 3, p. 184–187, 2011.
HOOD, Leroy; PRICE, Nathan D. Demystifying disease, democratizing health care. Science Translational Medicine, v. 6, n. 225, p. 225ed5, 2014.
TOPOL, Eric J. The creative destruction of medicine: how the digital revolution will create better health care. New York: Basic Books, 2012.
TOPOL, Eric J. Deep medicine: how artificial intelligence can make healthcare human again. New York: Basic Books, 2019.
VARMUS, Harold. The new era in cancer research. Science, v. 312, n. 5777, p. 1162–1165, 2006.
VARMUS, Harold; KUMAR, Sanjay; BURKE, Wylie. Cancer genomics and the future of oncology. Cell, v. 148, n. 1–2, p. 22–31, 2012.
WANG, Xiaoyuan; ZHANG, Feng. Molecular imaging in early disease detection. Nature Reviews Molecular Cell Biology, v. 15, n. 12, p. 779–792, 2014.
ZHANG, Aihua; SUN, Hui; WANG, Xijun. Emerging role of metabolomics in biomarker discovery and precision medicine. Clinical Chemistry, v. 58, n. 1, p. 50–60, 2012.
Descargas
Publicado
Número
Sección
Licencia

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.