POST-STROKE NEUROREGENERATION MEDIATED BY NANOMATERIALS: EMERGING EVIDENCE AND FUTURE PERSPECTIVES
DOI:
https://doi.org/10.63330/aurumpub.049-024Keywords:
Nanomaterials, Neuroprotection, Neuroregeneration, Stroke, Targeted therapyAbstract
Post-stroke neuroregeneration remains a major challenge in modern medicine due to the limited repair capacity of the central nervous system. This chapter aims to analyze emerging evidence on the use of nanomaterials to promote neural recovery after stroke. The methodology is based on a narrative literature review, including recent preclinical studies and experimental trials investigating nanoparticles, nanofibers, and controlled drug delivery systems. Results indicate that nanomaterials can enhance neurogenesis, angiogenesis, and modulation of inflammatory responses, while enabling targeted delivery of therapeutic agents to damaged brain tissue. These systems also show potential to overcome biological barriers such as the blood-brain barrier. It is concluded that, although promising, these advances still require robust clinical validation regarding safety, efficacy, and standardization. Translational studies are essential to enable future therapeutic applications.
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