SURGICAL AND FACIAL ASPECTS IN BECKWICH-WIEDEMANN SYNDROME: A LITERATURE REVIEW

Abstract

The study addresses Beckwith-Wiedemann Syndrome, a congenital genetic disorder characterized by facial alterations such as macroglossia, and the surgical approaches for its treatment. This is a literature review that synthesizes scientific evidence on the etiology, clinical manifestations, and surgical interventions. The main objective is to analyze the effectiveness of surgical techniques, such as partial glossectomy, in mitigating facial complications and improving patients' quality of life. The methodology involved a systematic search in databases such as PubMed, Cochrane Library, and Embase, using key terms related to the topic, with the inclusion of articles published between 2000 and 2025, prioritizing clinical studies, reviews, and meta-analyses, resulting in the analysis of 45 relevant publications. The results indicate that partial glossectomy resolves respiratory obstructions in about 87% of cases, with advances in minimally invasive techniques, such as robotic surgeries, reducing complications and recurrence, in addition to combined approaches with orthodontics improving aesthetic outcomes. The conclusion highlights the need for multidisciplinary teams to personalize treatments based on genetic subtypes, contributing to the comprehensive management of the syndrome and recommending prospective research to optimize surgical protocols.